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Updated: Jan 28, 2026

Spatial Separation of Molecular Conformers and Clusters
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ステキオメトリーは,アクチンシグナルタンパク質の相分離クラスタの活性を制御する

Lindsay B Case1,2, Xu Zhang2, Jonathon A Ditlev1,2

  • 1The HHMI Summer Institute, Marine Biological Laboratory, Woods Hole, MA 02543, USA.

Science (New York, N.Y.)
|March 9, 2019
PubMed
まとめ

生物分子凝縮物は,液体-液体相分離 (LLPS) によりタンパク質の活性を増強する. このプロセスは,N-WASPやArp2/3複合体のようなシグナル伝達タンパク質を膜に集中させることで,アクチンアセンブリを増加させます.

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