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Updated: Jan 28, 2026

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues

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KDEL受容体によるゴルギのERタンパク質のpH依存的回収の構造的基礎

Philipp Bräuer1, Joanne L Parker1, Andreas Gerondopoulos1

  • 1Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

Science (New York, N.Y.)
|March 9, 2019
PubMed
まとめ

この研究は,KDEL受容体の構造を明らかにし,これは,ゴルギ装置からエンドプラズマ網膜 (ER) のタンパク質を回収するのに不可欠です. トランスポーターのようなメカニズムとpH依存の相互作用は,真核細胞における効率的なタンパク質回収を保証する.

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