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Updated: Jan 27, 2026

A Melanoma Patient-Derived Xenograft Model
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ヒスティオサイト性腫瘍患者におけるMEK抑制の有効性

Eli L Diamond1,2, Benjamin H Durham3,4, Gary A Ulaner2,5

  • 1Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Nature
|March 15, 2019
PubMed
まとめ

ヒスティオサイト性腫瘍はMAPKのシグナル伝達に依存しています コビメチニブ (MEK阻害剤) の試験では,BRAF変異を有する患者およびそれのない患者で高い応答率を示し,すべてのヒスティオサイトーシス型に対する新しい治療法を提供した.

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