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Updated: Aug 15, 2026

Overlapping Peptide Library to Map Qa-1 Epitopes in a Protein
08:04

Overlapping Peptide Library to Map Qa-1 Epitopes in a Protein

Published on: December 20, 2017

OKT3モノクローナル抗体に対するヒトの免疫応答はオリゴクローナルである

L Chatenoud, M Jonker, F Villemain

    Science (New York, N.Y.)
    |June 13, 1986
    PubMed
    まとめ

    ミューリンのモノクローナル抗体OKT3は,移植における免疫抑制に使用されますが,抗体反応を引き起こします. この反応はオリゴクローナルであり,同一の特異性を持つ異なる抗体の連続使用が,感受性を克服することを示唆しています.

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