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Updated: Jan 27, 2026

A High-content Assay for Monitoring AMPA Receptor Trafficking
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ヘテロメアGluA1/2AMPA受容体と補助サブユニットTARP γ8との複合体の構造

Beatriz Herguedas1, Jake F Watson2, Hinze Ho2

  • 1Neurobiology Division, Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, UK. ig@mrc-lmb.cam.ac.uk hergueda@mrc-lmb.cam.ac.uk.

Science (New York, N.Y.)
|March 16, 2019
PubMed
まとめ

この研究は,TARP γ8を含む重要な脳受容体であるAMPA型グルタミン酸受容体 (AMPAR) の構造を明らかにした. この構造はGluA2が 学習と記憶に不可欠な 受容器のゲートとカルシウムフローを 制御する方法を説明します

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