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Updated: Jan 27, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

Published on: May 22, 2014

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機能的退化:様々な病原体酵素によるNLRP1炎症体の活性化メカニズム

Andrew Sandstrom1,2, Patrick S Mitchell1, Lisa Goers3,4,5

  • 1Division of Immunology and Pathogenesis, Department of Molecular & Cell Biology, and Cancer Research Laboratory, University of California, Berkeley, CA, USA.

Science (New York, N.Y.)
|March 16, 2019
PubMed
まとめ

炭毒素はNLRP1B炎症体を活性化し,その分解を誘発する. このプロテアソーム媒介のプロセスは,カスパース-1を活性化する断片を解放し,炎症ソーム活性化のための統一されたメカニズムを明らかにします.

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