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Updated: Jan 27, 2026

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
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Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

Published on: April 11, 2019

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ゲルミナル・センター・デリベイト・アンチボディは,動脈硬化症のプラークサイズと安定性を促進する

Monica Centa1, Hong Jin1, Lisa Hofste1

  • 1Departments of Medicine and Center for Molecular Medicine (M.C., H.J., L.H., S.H., A.B., R.B., N.J.V., S.L.E., S.V.B, D.Y.L., C.S., G.K.H., D.F.J.K., F.W., L.M., S.G.M.), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

Circulation
|March 22, 2019
PubMed
まとめ

抗体,特にIgGは,滑らかな筋肉細胞の増殖を促すことで,動脈硬化プラークのサイズと安定性を促進する. 抗体の喪失はより小さく,より脆弱なプラークにつながり,大動脈の分子アイデンティティと潜在的に動脈瘤の形成に影響を与えます.

キーワード:
B セルIgG について動脈硬化症発芽センタープラークの破裂滑らかな筋肉細胞の増殖

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Highly Resolved Intravital Striped-illumination Microscopy of Germinal Centers10:07

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