Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Vicinal Diols via Reductive Coupling of Aldehydes or Ketones: Pinacol Coupling Overview01:27

Vicinal Diols via Reductive Coupling of Aldehydes or Ketones: Pinacol Coupling Overview

2.2K
Wilhelm Rudolph Fittig discovered the pinacol coupling reaction in 1859. It is a radical dimerization reaction and involves the reductive coupling of aldehydes or ketones in the presence of hydrocarbon solvent to yield vicinal diols.
2.2K
Alkenes via Reductive Coupling of Aldehydes or Ketones: McMurry Reaction01:22

Alkenes via Reductive Coupling of Aldehydes or Ketones: McMurry Reaction

2.3K
The radical dimerization of ketones or aldehydes gives vicinal diols through a pinacol coupling reaction. However, the behavior of titanium metals used for the reaction as a source of electrons is unusual. When the reaction is carried out in the presence of titanium, diols can be isolated at low temperatures. Else titanium further reacts with diols, forming alkenes through the McMurry reaction.
2.3K
α-Hydroxy Ketones via Reductive Coupling of Esters: Acyloin Condensation Overview01:19

α-Hydroxy Ketones via Reductive Coupling of Esters: Acyloin Condensation Overview

3.3K
The pinacol and McMurry reactions involve the reductive coupling of ketones or aldehydes. Similarly, the bimolecular reductive coupling of two ester molecules in the presence of sodium metal in an aprotic solvent yields an α-hydroxy ketone product. The α-hydroxy ketone is also called acyloin, so the reaction is referred to as ‘acyloin condensation.’
3.3K
Oxidation-Reduction Reactions03:11

Oxidation-Reduction Reactions

75.3K
Oxidation–Reduction Reactions
75.3K
Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)01:20

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)

1.6K
Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others.
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
1.6K
Spin–Spin Coupling: Three-Bond Coupling (Vicinal Coupling)01:22

Spin–Spin Coupling: Three-Bond Coupling (Vicinal Coupling)

1.5K
Vicinal or three-bond coupling is commonly observed between protons attached to adjacent carbons. Here, nuclear spin information is primarily transferred via electron spin interactions between adjacent C‑H bond orbitals. This generally favors the antiparallel arrangement of spins, so 3J values are usually positive.
The extent of coupling depends on the C‑C bond length, the two H‑C‑C angles, any electron-withdrawing substituents, and the dihedral angle between the involved orbitals. The...
1.5K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

The Radicals cAAC<sup>Me</sup>·AlR<sub>2</sub>(thf) (R = Me, Et) as Synthons for Aluminum(II)-Centered Radicals AlR<sub>2</sub>.

Inorganic chemistry·2026
Same author

Planarity-induced emission of neutral 1,2,3-diazaborines mediated by C-H borylation.

Chemical communications (Cambridge, England)·2026
Same author

Synthesis, Bonding, and Reduction Chemistry of LBeBrY Complexes (L = Lewis Base, Y = Ar, NR<sub>2</sub>).

Inorganic chemistry·2026
Same author

Zerovalent transition-metal inverse-sandwich complexes of a diborataanthracene dianion.

Chemical science·2026
Same author

Organophosphinidene in a T-Shaped Environment.

Journal of the American Chemical Society·2026
Same author

Cooperative reactivity of halomethanes and -silanes at an A-frame complex: transannular addition <i>versus</i> bridging tetrylenes.

Chemical science·2026
Same journal

A native sulfur deposit in Gale crater, Mars.

Science (New York, N.Y.)·2026
Same journal

Coordinated demise of harmful algal blooms.

Science (New York, N.Y.)·2026
Same journal

Genetic effects put into context.

Science (New York, N.Y.)·2026
Same journal

Bacteria share proteins to survive antibiotics.

Science (New York, N.Y.)·2026
Same journal

Impacts shaped Earth's first continents.

Science (New York, N.Y.)·2026
Same journal

Erratum for the Report "Covalently bonded single-molecule junctions with stable and reversible photoswitched conductivity" by C. Jia <i>et al</i>.

Science (New York, N.Y.)·2026
関連記事をすべて見る

関連する実験動画

Updated: Jan 27, 2026

Surgical Size Reduction of Zebrafish for the Study of Embryonic Pattern Scaling
06:31

Surgical Size Reduction of Zebrafish for the Study of Embryonic Pattern Scaling

Published on: May 3, 2019

7.2K

二酸化窒素の還元結合

Marc-André Légaré1,2, Maximilian Rang1,2, Guillaume Bélanger-Chabot1,2

  • 1Institute for Inorganic Chemistry, Julius-Maximilians-Universität Würzburg, Am Hubland, 97074 Würzburg, Germany.

Science (New York, N.Y.)
|March 23, 2019
PubMed
まとめ
この要約は機械生成です。

研究者は,穏やかな条件下で2つの窒素分子 (N2) の予想外のオルガノボロン媒介結合を達成しました. この発見は,窒素連鎖の以前の理解に挑戦し,新しい合成の可能性を開きました.

さらに関連する動画

Quantitative Proteomics Using Reductive Dimethylation for Stable Isotope Labeling
11:53

Quantitative Proteomics Using Reductive Dimethylation for Stable Isotope Labeling

Published on: July 1, 2014

16.8K
A Practical Guide on Coupling a Scanning Mobility Sizer and Inductively Coupled Plasma Mass Spectrometer SMPS-ICPMS
11:18

A Practical Guide on Coupling a Scanning Mobility Sizer and Inductively Coupled Plasma Mass Spectrometer SMPS-ICPMS

Published on: July 11, 2017

11.2K

関連する実験動画

Last Updated: Jan 27, 2026

Surgical Size Reduction of Zebrafish for the Study of Embryonic Pattern Scaling
06:31

Surgical Size Reduction of Zebrafish for the Study of Embryonic Pattern Scaling

Published on: May 3, 2019

7.2K
Quantitative Proteomics Using Reductive Dimethylation for Stable Isotope Labeling
11:53

Quantitative Proteomics Using Reductive Dimethylation for Stable Isotope Labeling

Published on: July 1, 2014

16.8K
A Practical Guide on Coupling a Scanning Mobility Sizer and Inductively Coupled Plasma Mass Spectrometer SMPS-ICPMS
11:18

A Practical Guide on Coupling a Scanning Mobility Sizer and Inductively Coupled Plasma Mass Spectrometer SMPS-ICPMS

Published on: July 11, 2017

11.2K

科学分野:

  • 無機化学
  • 有機金属化学
  • 材料科学

背景:

  • 窒素分子 (N2) の連鎖は,強い三重結合と低いN-N単一結合エンタルピーのために通常不利である.
  • 以前の合成方法は 超高圧やプラズマのような 極端な条件を必要としていました
  • 自然なN2結合は,放射線条件下でイオノスフィアで発生する.

研究 の 目的:

  • より穏やかな条件下で窒素分子 (N2) の連鎖を実現するための新しい方法を探求する.
  • 窒素結合反応を媒介するオルガノボロン化合物の役割を調査する.
  • 新しい窒素豊富な化合物を合成し,特徴づけること.

主な方法:

  • 2つの窒素分子 (N2) のオルガノボロン媒介による還元結合
  • 周囲の環境下での反応
  • 生成した複合体とその陽子派生体の結晶学的な特徴.

主要な成果:

  • 2つのボロンセンターを結ぶ橋渡し [N4]2− 鎖を備えた複合体の成功合成.
  • 低値ボロン結合 N2 ユニットの単段階の還元結合の実証
  • 独特のN4鎖構造とその陽子化された形態の結晶学的確認.

結論:

  • オーガノボロン化合物は,環境に近い条件下で窒素分子 (N2) の挑戦的な連鎖を容易にする.
  • この研究は,窒素に富んだ化合物を合成するための新しい経路を提供します.
  • 発見は窒素固定と窒素鎖化学の範囲を拡大する.