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Author Spotlight: Understanding DNA Damage Response in Mammalian Oocytes and Preimplantation Embryos
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単純なヌクレアース誘発の二重鎖断裂による精密な治療用遺伝子修正

Sukanya Iyer1, Sneha Suresh1, Dongsheng Guo2,3

  • 1Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.

Nature
|April 5, 2019
PubMed
まとめ

この研究は,マイクロ複製変異のための新しい遺伝子修正方法を導入します. DNAの断裂を起こすことで 病気を引き起こす配列を効率的に 野生型に戻し より単純な治療法を提供します

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