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Updated: Jan 26, 2026

Measuring mRNA Levels Over Time During the Yeast S. cerevisiae Hypoxic Response
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PTCを含むmRNAは,Upf3aとCOMPASSのコンポーネントを通じて遺伝的補償応答を誘発する

Zhipeng Ma1, Peipei Zhu1, Hui Shi2,3

  • 1MOE Key Laboratory of Biosystems Homeostasis & Protection and Innovation Center for Cell Signaling Network, College of Life Sciences, Zhejiang University, Hangzhou, China.

Nature
|April 5, 2019
PubMed
まとめ

遺伝子補償反応 (GCR) は,Upf3aとCOMPASS複合体を含む早期終結コドン (PTC) を含むmRNAによって誘発される. このメカニズムは現象的差異を説明し,遺伝的疾患の治療戦略を提供します.

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