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関連する概念動画

Oromucosal as an Alternative Method for Administration of Cannabis Products in Rodents03:43

Oromucosal as an Alternative Method for Administration of Cannabis Products in Rodents

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Oral administration via gavage in rodents can induce distress associated with restraint. We explored oromucosal/buccal administration of CBD-enriched Cannabis extract, where rats were treated for 15 days with the extract at 3 mg/kg/day. Treatments were administered orally with a micropipette, using an affectionate touch technique to handle the...
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Establishment and Validation of a Rat Model of Pulmonary Arterial Hypertension Associated with Pulmonary Fibrosis07:11

Establishment and Validation of a Rat Model of Pulmonary Arterial Hypertension Associated with Pulmonary Fibrosis

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Here, the method of inducing pulmonary arterial hypertension associated with pulmonary fibrosis (PF-PH) rat model by injecting bleomycin into the airway is introduced. We also provide a step-by-step approach to validate this animal...
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Synthesis of a Deuterated Standard for the Quantification of 2-Arachidonoylglycerol in Caenorhabditis elegans14:25

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This work describes a robust and straightforward method to detect and quantify the endocannabinoid 2-arachidonoylglycerol (2-AG) in C. elegans. An analytical deuterated standard us prepared and used for the quantification of 2-AG by isotopic dilution and liquid chromatography-electrospray ionization-tandem mass spectrometry...
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Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats09:37

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Here we describe a detailed protocol for invasive measurements of hemodynamic parameters including portal pressure, splanchnic blood flow, and systemic hemodynamics in order to characterize the portal hypertensive syndrome in...
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The Mesenteric Lymph Duct Cannulated Rat Model: Application to the Assessment of Intestinal Lymphatic Drug Transport13:17

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Here we describe a technique to cannulate the mesenteric lymph duct in rats which enables quantification of lipid and drug transport via the lymphatic system following intestinal delivery. The technique can be adapted to assess mesenteric lymph concentrations and/or transport of fluid, immune cells, peptides, proteins and lipophilic...
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Updated: Jan 11, 2026

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中部内皮質におけるオブジェクトベクトルコーディング

Øyvind Arne Høydal1, Emilie Ranheim Skytøen2, Sebastian Ola Andersson2

  • 1Kavli Institute for Systems Neuroscience and Centre for Neural Computation, Norwegian University of Science and Technology (NTNU), Trondheim, Norway. oyvind.a.hoydal@ntnu.no.

Nature
|April 5, 2019
PubMed
まとめ
この要約は機械生成です。

研究者らは脳内側側皮質に 対象ベクトル細胞と呼ばれる 新しい脳細胞を発見しました これらの細胞は物体の距離と方向を 基に空間情報をコードし 航行や空間記憶の理解を 進めるのです

さらに関連する動画

The Mesenteric Lymph Duct Cannulated Rat Model: Application to the Assessment of Intestinal Lymphatic Drug Transport
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Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
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関連する実験動画

Last Updated: Jan 11, 2026

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科学分野:

  • 神経科学
  • 認知科学

背景:

  • 脳のナビゲーションシステムは ヒッポカンプスと中枢内皮質を含む 場所とグリッド細胞のような 特殊な細胞を使って 自己位置をマップします
  • 現在の理解はシンプルな環境での研究によって制限されていて,自然でオブジェクトが豊富な環境を反映していません.
  • 動物はオブジェクトベースのベクトル情報をナビゲーションに使用しますが 神経機構は不明です

研究 の 目的:

  • 複雑でオブジェクトで満たされた環境で空間をどのように表すかを調査する.
  • 分離されたオブジェクトを使用してベクトルベースのナビゲーションをサポートするニューラル基板を識別します.

主な方法:

  • ネズミの脳内側皮質のニューロンの記録で 分離された物体を持つ環境をナビゲートします
  • オブジェクトの距離と方向に関連した神経発射パターンの分析.

主要な成果:

  • "オブジェクトベクトル細胞"と呼ばれる中部内皮質の神経細胞の有意な集団が特定されました.
  • 特定の距離と方向をコードする 発射パターンを表しています
  • オブジェクトベクトル細胞は,様々なオブジェクトタイプ,サイズ,形に一貫して反応します.

結論:

  • オブジェクトベクトル細胞は,中央の腸内皮質における空間的コーディングの主要なメカニズムを表しています.
  • この発見は,脳が物中心のベクトル情報を使って 航海する高度な能力を強調しています
  • この研究は 伝統的な場所とグリッドの概念を超えて 神経表現に関する知識を広げています