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Updated: Jan 26, 2026

Study of Protein-protein Interactions in Autophagy Research
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ATG8結合のUIMタンパク質は,新種のオートファギーアダプターと受容体を定義する

Richard S Marshall1, Zhihua Hua2, Sujina Mali1

  • 1Department of Biology, Washington University in St. Louis, St. Louis, MO 63130, USA.

Cell
|April 9, 2019
PubMed
まとめ

研究者は,ユビキチン相互作用モチーフ (Ubiquitin-interacting motif,UIM) のような配列を用いて,オートファジー中にATG8/LC3に結合する新しい種類のタンパク質を発見した. この発見は,選択的オートファギーの理解を拡大し,オートファギの膀動力の新しい調節体を特定します.

キーワード:
AIM についてATG8 についてATG8相互作用モチーフアラビドプシスCDC48/p97 についてLC3 相互作用する領域LDS についてLIR についてLIR/AIMドッキングサイトUDS についてUIM についてUIMドッキングサイトオートファジーウビキチンと相互作用するモチーフイースト

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