ディアリル-λ3-クローラン: アリルカチオン等価体としての多用途合成とユニークな反応性
Misuzu Nakajima1, Kazunori Miyamoto1, Keiichi Hirano1
1Graduate School of Pharmaceutical Sciences , The University of Tokyo , 7-3-1 Hongo , Bunkyo-ku, Tokyo 113-0033 , Japan.
Journal of the American Chemical Society
|April 11, 2019
まとめ
新しい合成法では,クロロアレンとメシチルディアゾニウム塩からダイアリクロニウム/λ3-クロランを生成する. これらの化合物は,電愛性アリレーションおよびハロゲン交換反応においてユニークな反応性を示す.
科学分野:
- 有機化学
- 合成化学
- 有機金属化学
背景:
- ダイアリクロニウム塩と λ3-クローランは重要な合成中間物質である.
- 合成するための既存の方法は,範囲が制限されているか,厳しい条件を必要とします.
研究 の 目的:
- ダイアリクロニウム/λ3-クローランの多用途で高生産性の合成を開発する.
- 合成されたダイアリクロニウム/λ3-クローランの反応性を調べる.
主な方法:
- 様々なクロロアレン (ArCl,ArBr,ArI) とメシチルディアゾニウムテトラキス (pentafluorophenyl) ボラートの反応
- 軽度の反応条件が採用された.
主要な成果:
- 幅広いダイアリクロニウム/λ3-クローランの合成に成功した.
- 弱いヌクレオフィルの分子間電気結合を含むユニークな反応性を示した.
- クロランとハロゲンの交換反応が示されました
結論:
- 開発された方法は,ダイアリクロニウム/λ3-クローランへの多用途で高生産性の経路を提供します.
- 合成された化合物は,合成用途のための新しい反応性を提供します.
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