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Updated: Jan 26, 2026

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SiRA: 生細胞超解像度RNAイメージングのためのシリコンロダミン結合アプタマー

Regina Wirth1, Peng Gao2,3, G Ulrich Nienhaus2,3,4,5

  • 1Institute of Pharmacy and Molecular Biotechnology (IPMB) , Heidelberg University , 69120 Heidelberg , Germany.

Journal of the American Chemical Society
|April 16, 2019
PubMed
まとめ

研究者は,シリコンロダミン (SiR) 染料を結合する新しいRNAアプタマー (SiRA) を開発し,生細胞RNAイメージングのために明るい,光安定の遠赤色光放射を可能にしました. このシステムは,超高解像度顕微鏡を用いて,細菌と生細胞のRNAの視覚化を強化します.

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