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Updated: Jan 26, 2026

Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry
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脂肪酸輸送タンパク質2 がん中の中性粒子を再プログラムする

Filippo Veglia1, Vladimir A Tyurin2, Maria Blasi3

  • 1Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA, USA.

Nature
|April 19, 2019
PubMed
まとめ

脂肪酸輸送タンパク質2 (FATP2) は,多形態核ミエロイド由来抑制細胞 (PMN-MDSC) の免疫抑制機能を駆動する. FATP2を阻害することで,これらの細胞を標的とし,がん治療の有効性を高め,腫瘍の進行を遅らせます.

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