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生まれてから成人期までの体重と肥満の多遺伝子予測

Amit V Khera1, Mark Chaffin2, Kaitlin H Wade3

  • 1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Division of Cardiology, Massachusetts General Hospital, Boston, MA 02114, USA; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

Cell
|April 20, 2019
PubMed
まとめ

遺伝的傾向は肥満のリスクに大きな影響を与えます 200万のDNA変異を用いた新しい多遺伝子予測器は 遺伝的感受性を定量化し,出生から成人期までの 体重と重度の肥満リスクのグラデーションを明らかにしています

キーワード:
イギリスのバイオバンク体重指数遺伝的リスクの予測ゲノム医学人間遺伝学メラノコルチン4受容体多遺伝子スコア重度の肥満体重

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