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Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis
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フィラミンAをターゲットにすることで,マクロファージの活動と動脈硬化が低下する

Sashidar Bandaru1, Chandu Ala1, Reza Salimi1

  • 1Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine (S.B., C.A., R.S., S.D., J.V.d.E., E.L., L.M.A.), Sahlgrenska Academy, University of Gothenburg, Sweden.

Circulation
|April 25, 2019
PubMed
まとめ

マクロファージのフィラミンA (FLNA) は細胞機能に不可欠であり,動脈硬化症を軽減します. FLNAの分裂を阻害することは,この心血管疾患の治療のための新しい治療戦略を提供するかもしれません.

キーワード:
細胞骨格エンドアテレクトミー脂質モデル 動物

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