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Updated: Jan 25, 2026

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications
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活性化された刺激性Gタンパク質に結合する膜アデニルサイクラスの構造

Chao Qi1,2, Simona Sorrentino3, Ohad Medalia3,4

  • 1Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.

Science (New York, N.Y.)
|April 27, 2019
PubMed
まとめ

膜アデニルサイクラゼ9 (AC9) の構造は,Gタンパク質との相互作用を明らかにします. この発見は,細胞シグナル伝達における循環性アデノシンモノフォスファート (cAMP) 産生の調節に関する洞察を提供します.

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