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Updated: Jan 25, 2026

Functional Characterization of Na+/H+ Exchangers of Intracellular Compartments Using Proton-killing Selection to Express Them at the Plasma Membrane
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Functional Characterization of Na+/H+ Exchangers of Intracellular Compartments Using Proton-killing Selection to Express Them at the Plasma Membrane

Published on: March 30, 2015

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進化的に保存された膜タンパク質であるPACは,陽子活性化塩化チャネルである

Junhua Yang1, Jianan Chen1, Maria Del Carmen Vitery1

  • 1Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Science (New York, N.Y.)
|April 27, 2019
PubMed
まとめ

研究者らは,PAC (TMEM206) を,陽子活性化塩素電流 (ICl,H) に対して決定的であると特定した. この発見は 細胞の酸性への反応や 脳卒中などの疾患における 細胞の役割を明らかにしています

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