妊娠中の体重増加と母親と乳児の不良の結果との関連
, Ellis Voerman1,2, Susana Santos1,2
1Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
JAMA
|May 8, 2019
まとめ
妊娠前の体重指数 (BMI) によって最適な妊娠体重増加は異なります. この研究では,異なるBMIカテゴリーの特定の体重増加範囲を特定し,母親と乳児の不良結果を軽減しました.
科学分野:
- 母親と乳児の健康
- 産婦人科
- 公衆衛生
背景:
- 妊娠中の体重増加 (GWG) の不十分と過剰の両方が,母親と乳児の有害な結果と関連しています.
- 妊娠前の全体量指数 (BMI) において最適なGWGの範囲は明確に定義されていません.
研究 の 目的:
- GWGの範囲と母親/乳児の悪影響との関連を分析する.
- 妊娠前の様々なBMIカテゴリーの最適なGWG範囲を決定する.
主な方法:
- 25のコホート研究から196,670人の女性を対象とした個々の参加者レベルのメタ分析.
- 最適なGWGの範囲は,有害な結果の最も低いリスクと関連しているものとして定義されました.
- 3,505人の追加参加者のデータを用いて検証した.
主要な成果:
- 副作用のリスクはGWGと妊娠前のBMIによって有意に変化した.
- 理想的なGWGの範囲は,各BMIカテゴリーで特定されました.例えば,正常体重は10. 0から16. 0kg,肥満は2. 0から6. 0kgです.
- これらの範囲は,アウトカムに対する限られた予測値を示した.
結論:
- GWGの推奨は,個々の妊娠前のBMIに合わせる必要があります.
- 最適な範囲が特定されましたが,特定の有害な結果に対する予測能力は中等です.
- 発見はGWGに関する産前カウンセリングを参考にすることができます.
さらに関連する動画
06:39Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
3.5K
07:13Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C
Published on: March 25, 2016
19.5K
関連する概念動画
Gain
399
Gain and phase shift are properties of linear circuits that describe the effect a circuit has on a sinusoidal input voltage or current. The circuit's behavior that contains reactive elements will depend on the frequency of the input sinusoid. As a result, it is observed that the gain and phase shift will all be frequency functions.
Gain:
Suppose Vin is the input and Vout is the output signal to a circuit.
Gain:
Suppose Vin is the input and Vout is the output signal to a circuit.
399
Weighted Mean
6.2K
While taking the arithmetic, geometric, or harmonic mean of a sample data set, equal importance is assigned to all the data points. However, all the values may not always be equally important in some data sets. An intrinsic bias might make it more important to give more weightage to specific values over others.
For example, consider the number of goals scored in the matches of a tournament. While computing the average number of goals scored in the tournament, it may be more important to...
For example, consider the number of goals scored in the matches of a tournament. While computing the average number of goals scored in the tournament, it may be more important to...
6.2K
Diabetes Mellitus: Type 2 and Gestational
4.4K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.4K
Predicting Reaction Outcomes
10.4K
Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
10.4K
Local Anesthetics: Adverse Effects
781
While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
781
Outcomes of Glycolysis
106.8K
Nearly all the energy used by cells comes from the bonds that make up complex organic compounds. These organic compounds are broken down into simpler molecules, such as glucose. As a result, cells extract energy from glucose over many chemical reactions—a process called cellular respiration.
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
106.8K
