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Updated: Jan 25, 2026

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ヒトDNAポリメラーゼ μは,複数のMn2+を媒介するメカニズムを使用できる

Yao-Kai Chang1,2, Ya-Ping Huang1, Xiao-Xia Liu1

  • 1Institute of Biological Chemistry, Academia Sinica , 128 Academia Road Sec. 2 , Nankang, Taipei 115 , Taiwan.

Journal of the American Chemical Society
|May 9, 2019
PubMed
まとめ

DNAポリメラーゼ mu (Pol μ) は,金属結合核酸のための非正規のプリバインディング経路を使用し,マグネシウムよりもマンガンを好みます. このメカニズムはDNAの修復と複製における 多様な機能に不可欠です

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