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Updated: Jan 24, 2026

Genome-wide Analysis using ChIP to Identify Isoform-specific Gene Targets
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Genome-wide Analysis using ChIP to Identify Isoform-specific Gene Targets

Published on: July 7, 2010

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単細胞ゲノミクスは,自閉症における細胞タイプ特有の分子変化を特定する

Dmitry Velmeshev1,2, Lucas Schirmer3,4,5, Diane Jung3,2

  • 1Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA. dmitry.velmeshev@ucsf.edu arnold.kriegstein@ucsf.edu.

Science (New York, N.Y.)
|May 18, 2019
PubMed
まとめ

自閉症の研究は,特に興奮神経とマイクログリアにおける特定の脳細胞変化を明らかにし,シナプス信号伝達に影響を与え,臨床的重症と相関しています. これらの発見は 皮質回路の分子変化を 自閉症の行動と結びつけています

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