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ランダム化,アクティブ・コントロール,オープンフェーズ3試験

Erik A Imel1, Francis H Glorieux2, Michael P Whyte3

  • 1Department of Medicine and Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.

Lancet (London, England)
|May 21, 2019
PubMed
まとめ

伝統的な治療法と比較して,X関連低リン酸性血症の小児では,ブルースマブがラキットの重症度および成長を有意に改善しました. この研究は,この稀な遺伝疾患に対するより効果的な治療法として,ブルースマブを強調しています.

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Understanding the working function of different types of controllers can be illustrated with practical analogies, such as adjusting a stereo's volume equalizer. Cranking up the bass involves a phase-lead controller, which functions as a high-pass filter, while increasing the treble uses a phase-lag controller, which acts as a low-pass filter. PD controllers, similar to high-pass filters, enhance the system's response to high-frequency components. PI controllers, akin to low-pass...
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