ポリエステルおよびポリカーボネートライブラリの迅速かつスケーラブルな合成のためのプログラム可能な高スループットプラットフォーム
Binhong Lin1, James L Hedrick2, Nathaniel H Park2
1Department of Chemistry , Stanford University , Stanford , California 94305 , United States.
Journal of the American Chemical Society
|May 24, 2019
まとめ
研究者は連続フロー反応器と有機触媒を用いて 多様なポリエステルやポリカーボネート材料を作るための 迅速でスケーラブルな方法を開発しました この方法では ポリマーの構造を精密に制御し 材料の特性を調整します
科学分野:
- ポリマー化学
- 材料科学
- 有機合成
背景:
- マクロ分子材料の性質は,構成,構造,分子量,分布の正確な制御に依存しています.
- 既存の合成方法は,完全な構造-性質の景観を探索するために必要な再現性,スケーラビリティ,およびプログラム性が欠けていることが多い.
研究 の 目的:
- ポリエステルとポリカーボネートホモポリマーとブロックコポリマーを合成するための迅速で制御可能な方法を開発する.
- 有機触媒と連続フロー反応器を活用して マクロ分子合成を正確に制御する
主な方法:
- プログラムされた連続流動型原子炉で調節可能な高活性有機触媒を用いる.
- 短期滞在時間 (6 ms) と高回転周波数 (TOF = 24,000,000 h−1) を有する高度に制御されたポリメリゼーションを達成した.
- 効率的なブロックコポリマー合成のためのインフロー触媒スイッチ戦略を実装した.
主要な成果:
- ポリエステルとポリカーボネートホモポリマーとブロックコポリマーのライブラリを高い効率と制御で成功裏に生成しました.
- 分間に数十グラムの速さでポリマーを生産する 拡張性を示した.
- 反応性の異なるモノマーを使って たった9分で 100個の異なるブロックコポリマーを素早く合成しました
結論:
- 有機触媒と連続フロー炉の組み合わせは プログラム可能なマクロ分子合成のための強力なプラットフォームを提供します
- この方法は,ポリエステルとポリカーボネートの構造-特性関係を迅速に探求することを可能にします.
- 開発された技術は,高度なポリマー材料を作成するための堅牢でスケーラブルなアプローチを提供します.
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