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Updated: Jan 24, 2026

Isolation of High-density Lipoproteins for Non-coding Small RNA Quantification
10:39

Isolation of High-density Lipoproteins for Non-coding Small RNA Quantification

Published on: November 28, 2016

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低密度リポプロテイン受容体発現の増加による低密度リポプロテインコレステロール低下

Marjolein A W van den Boogert1,2, Lars E Larsen2,3, Lubna Ali2

  • 1Departments of Vascular Medicine (M.A.W.v.d.B., J.K., G.M.D.-T., E.S.G.S., A.G.H.), Amsterdam University Medical Centers, location AMC, The Netherlands.

Circulation
|May 24, 2019
PubMed
まとめ

遺伝的糖分化障害 (CDG) のN- 糖分化欠陥は,LDL受容体の活性とコレステロールのクリアランスの増加につながります. これは,N-グリコシレーションをターゲットにすることで,LDLコレステロールと心血管疾患のリスクを低下させるための新しい治療法を提供できることを示唆しています.

キーワード:
コレステロール血糖溶解の先天性障害グライコシレーション低ベタリポプロテイン症受容体,LDLステロール規制要素結合タンパク質2

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