青春期 の 体量指数 の 増加 は,中年 期 の 心筋 病 症 の 危険 を 予測 する
Josefina Robertson1,2, Maria Schaufelberger3,2, Martin Lindgren3,2
1Department of Public Health and Community Medicine/Primary Health Care (J.R., M.A.), Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden.
Circulation
|May 29, 2019
まとめ
青少年の軽度の肥満は 成人の心筋病,特に膨張型のリスクを大幅に高めます. 青年期における体重管理は 心臓の再形成と心不全を予防するために不可欠です
科学分野:
- 心臓病科
- 公衆衛生
- エピデミオロジー
背景:
- 心筋病は若者の心不全の原因として 増加しています
- 特に若者における心筋病のリスクに影響を及ぼす 変えられるライフスタイルの要因については さらに調査が必要である.
- 青春期における肥満は 早期の心不全を予測する 既知の要因です
研究 の 目的:
- 青年期における肥満と成人期における心筋病の発症リスクとの関連を調べる
- 青春期におけるボディマス指数 (BMI) と特定のタイプの心筋病の関連性を調べる.
主な方法:
- 1668893人の青少年を対象とした全国的な,レジスタに基づく前向きなコホート研究.
- ベースラインデータには,BMI,血圧,フィットネス,筋肉の強さが含まれていた.
- カーディオミオパシー診断は46年間の追跡期間を通じて追跡され,分析にはコックス比例リスクモデルが使用されました.
主要な成果:
- 青春期におけるBMI増加と心筋病,特に拡張性心筋病のリスクの増加との間に強い関連性が見られた.
- 正常範囲のBMI (22.5~24. 9 kg/ m2) でさえ,リスクは1. 38倍に増加した.
- BMI ≥35kg/ m2は,BMI18. 5〜19. 9kg/ m2と比較して,リスクが8倍以上増加した.
結論:
- 青年の体重増加は,たとえ軽度であっても,成人の心筋病のリスクの増加と関連しています.
- これらの発見は,若者の体重管理が 心血管の健康に与える重要性を強調しています.
- 肥満は,不良な心臓の改造に重要な独立した寄与因子であり,不良性心臓病とは関係ありません.
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