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Updated: Jul 22, 2026

High-throughput Purification of Affinity-tagged Recombinant Proteins
07:44

High-throughput Purification of Affinity-tagged Recombinant Proteins

Published on: August 26, 2012

ユカリオットRNAポリメラーゼIプロモーター結合は,転写開始因子とのタンパク質接触によって導かれ,DNA配列独立である

P Kownin, E Bateman, M R Paule

    Cell
    |August 28, 1987
    PubMed
    まとめ

    RNAポリメラーゼIは,DNA配列ではなく,転写開始因子 (TIF) とのタンパク質-タンパク質相互作用を通じて,リボソームRNA遺伝子プロモーターと結合する. しかしながら,転写の開始は,開始部位にある特定のDNA配列に依存する.

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