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Updated: Jan 24, 2026

Intestinal Epithelial Regeneration in Response to Ionizing Irradiation
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URIは,電離放射線中に腸の構造を維持するために必要です

Almudena Chaves-Pérez1, Mahmut Yilmaz1, Cristian Perna2

  • 1Cancer Cell Biology Programme, Growth Factors, Nutrients and Cancer Group, Centro Nacional Investigaciones Oncológicas, CNIO, Madrid 28029, Spain.

Science (New York, N.Y.)
|June 1, 2019
PubMed
まとめ

非従来のプリフォルディンRPB5インタラクター (URI) は,放射線誘発性胃腸症候群 (GIS) に対して保護します. URI減少は,標識保持細胞のc-MYCを活性化することによって,マウスをIRに敏感にし,組織修復の重要な要因としてURIを強調します.

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