関連する実験動画

Updated: Jan 23, 2026

A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening
08:34

A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening

Published on: October 16, 2015

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変異性トランスレション合成を標的とする小分子は,化学療法を改善する

Jessica L Wojtaszek1, Nimrat Chatterjee2, Javaria Najeeb1

  • 1Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA.

Cell
|June 11, 2019
PubMed
まとめ

研究者は,変異性転化合成 (TLS) を標的とする新しい小分子阻害剤,JH-RE-06を開発した. 薬剤耐性を阻害し,治療による変異を減らすことで, 化学療法の有効性を高めています.

キーワード:
POL ζREV1 についてREV7 について化学抵抗性化学療法シスプラチントランスレション合成

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