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Updated: Jan 23, 2026

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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トランポゾンでコードされたCRISPR-Casシステムは,RNA誘導DNA統合を直接行います

Sanne E Klompe1, Phuc L H Vo2, Tyler S Halpin-Healy1

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Nature
|June 13, 2019
PubMed
まとめ

バクテリアのトランポゾンは,DNA統合のためのCRISPR-Casシステムを再利用し,二重鎖の断絶なしにプログラム可能な遺伝子挿入を可能にしました. この発見は 精密なゲノム操作のための 新しいツールを提供します

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