TOX,T寿

Francesca Alfei1, Kristiyan Kanev1, Maike Hofmann2

  • 1Division of Animal Physiology and Immunology, School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.

Nature
|June 18, 2019
PubMed
まとめ

ティモサイト選択に関連した高移動性グループボックス (TOX) タンパク質は,慢性感染症の際にT細胞の枯渇に不可欠です. TOXはT細胞の機能不全を維持し,免疫療法とウイルスや腫瘍に対する保護免疫に影響を与えます.

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