社会的に相互作用するコウモリの脳内の相関神経活動
Wujie Zhang1, Michael M Yartsev1
1Helen Wills Neuroscience Institute and Department of Bioengineering, UC Berkeley, Berkeley, CA 94720, USA.
Cell
|June 25, 2019
まとめ
バットにおける神経活動が 社会的相互作用の間に高度に相関し 脳の間の同期が 社会的行動の鍵であることを示しています この相関関係には長い時間軸があり 高周波の脳信号が最も強いのです
科学分野:
- 神経科学
- 行動生物学
- 計算神経科学
背景:
- 社会的相互作用の背後にある 神経機構を理解することは 極めて重要です
- これまでの研究では 自然な社会的行動における 脳の交差神経のダイナミクスについて 詳細に説明できませんでした
研究 の 目的:
- 蝙蝠の自然な社会的な相互作用の間の 神経のダイナミクスの関係を調査する.
- 脳間の相関が起こる時間スケールと神経活動のレベルを 決定する.
主な方法:
- 様々な社会的な交流の際に 双方のコウモリから同時に無線で 電気生理学的記録を記録する
- 異なる時間スケール (秒から時間) にわたる神経活動相関の分析.
- 局所的なフィールドポテンシャル (LFP) とスパイク活動における相関の検討.
主要な成果:
- 長い期間,ペアリングされたコウモリ間の 驚くべき神経活動相関が観察されました.
- 相関の強さは共有された社会的環境に依存し,高周波のLFP (> 30 Hz) で顕著でした.
- ニューラル相関レベルは,社会的相互作用の程度と,相互作用の開始前に共変した.
結論:
- 脳の相関関係は 自然な社会的相互作用の 本質的な側面です
- 高周波のLFPと局所的なスパイキング活動は このニューラル・シンクロニーにとって重要な領域です
- 社会的行動における脳間相関の機能的役割を探求するための基礎を提供している.
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