社会的に相互作用する動物の脳における相関神経活動と行動のエンコーディング
Lyle Kingsbury1, Shan Huang1, Jun Wang1
1Department of Biological Chemistry and Department of Neurobiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Cell
|June 25, 2019
まとめ
ネズミは 社会的交流の際に 脳活動が同期され 個人の行動や 交際相手の行動に繋がります 脳の間の同期は 将来の社会的動態と支配を予測し 集団の行動を調整する 重要なメカニズムを明らかにします
科学分野:
- 神経科学
- 社会的行動
- システム生物学
背景:
- 社会的なやり取りは 複雑でダイナミックなフィードバックに依存しています
- 相互作用する脳の特性を理解することは 社会的意思決定に不可欠です
研究 の 目的:
- ネズミの社会的相互作用中の神経活動における脳間相関を調査する.
- 神経のシンクロニーと 社会的行動の関係を見極めるため
主な方法:
- 相互作用するマウスのペアで同時に微視内視鏡でカルシウム画像を撮る.
- 前頭前皮質の神経活動の分析
- 個人の行動と社会的行動との神経活動の相関関係
主要な成果:
- ネズミは社会的な交流中に 前頭前皮質の神経活動において 脳間相関を示す.
- シンクロニティは 自己とパートナー行動を 暗号化するニューロンの集団によって 駆動されます
- 脳の間の相関は 将来の社会的相互作用と支配的階層を予測します
結論:
- ネズミの脳間のシンクロニティの証拠です
- 単細胞のメカニズムが 脳間の神経の同期を 明らかにする
- 社会的相互作用を調整するためのシステムプロパティとして脳間神経結合を確立します.
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