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Updated: Jan 22, 2026

Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET
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ニューロテンシン受容体1-Gi1複合体のコンフォルマショナルトランジション

Hideaki E Kato1,2, Yan Zhang1,3,4, Hongli Hu1,3

  • 1Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.

Nature
|June 28, 2019
PubMed
まとめ

研究者らはGタンパク質に結合したニューロテンシン受容体1 (NTSR1) を視覚化し,2つの異なる構造状態を明らかにした. これらの発見は,複雑なGタンパク質活性化経路に関する新しい洞察を提供します.

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