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Updated: Jan 22, 2026

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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ヒトミトコンドリアDNAポリメラーゼにおけるポリメラーゼとエクソヌクレアゼ活性部位間のネットワーク通信

Mark L Sowers, Andrew P P Anderson1, James O Wrabl2

  • 1Program of Quantitative and Computational Biosciences , Baylor College of Medicine , Houston , Texas 71115 , United States.

Journal of the American Chemical Society
|June 29, 2019
PubMed
まとめ

人間のミトコンドリアDNAポリメラーゼ (Pol γ) は,高精度複製のために2つの活性サイトを使用します. 新しい研究では これらの部位を繋ぐ エネルギー結合ネットワークが ニュクレオチドの区別を強めていることが 明らかになりました

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