関連する実験動画

Updated: Jan 22, 2026

Optical Tweezers to Study RNA-Protein Interactions in Translation Regulation
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Optical Tweezers to Study RNA-Protein Interactions in Translation Regulation

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浸透性クロマチン-RNA結合タンパク質の相互作用は,RNAベースの転写の調節を可能にします

Rui Xiao1, Jia-Yu Chen2, Zhengyu Liang3

  • 1Department of Cellular and Molecular Medicine, Institute of Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Medical Research Institute, Wuhan University, Wuhan, Hubei 430071, China.

Cell
|June 29, 2019
PubMed
まとめ

RNA結合タンパク質 (RBPs) は,遺伝子転写とクロマチンの活性を直接調節することがますます判明しています. この研究は,遺伝子の発現に影響を与える,活発なヒトゲノム領域,特にプロモーターに広範囲にわたるRBP結合を明らかにしています.

キーワード:
RBP-TFの共同使用RNAベースの転写制御RNA結合タンパク質YY1媒介のDNAループクロマチン結合機能的ゲノミクス

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