関連する実験動画

Updated: Jan 22, 2026

Studying the Protein Quality Control System of D. discoideum Using Temperature-controlled Live Cell Imaging
06:09

Studying the Protein Quality Control System of D. discoideum Using Temperature-controlled Live Cell Imaging

Published on: December 2, 2016

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グリシン特異のN-デグロン経路は,タンパク質N-ミリストイレーションの品質制御を媒介する

Richard T Timms1,2, Zhiqian Zhang1,2, David Y Rhee3

  • 1Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.

Science (New York, N.Y.)
|July 6, 2019
PubMed
まとめ

研究者らは,N端のグリシンを標的とした新しいタンパク質分解経路を発見した. この経路は,Cul2ZYG11BとCul2ZER1を巻き込み,N-ミリスチル化タンパク質のアポトーシスと品質管理に役割を果たしている.

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