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設計された酵素の進化過程における負の活性化熱能力の出現

H Adrian Bunzel1, Hajo Kries1, Luca Marchetti1

  • 1Laboratory of Organic Chemistry , ETH Zurich , 8093 Zurich , Switzerland.

Journal of the American Chemical Society
|July 9, 2019
PubMed
まとめ

研究室での進化は 主にエンタルピックの変化によって 酵素活性が劇的に向上しました 進化した酵素は,自然な酵素の進化を反映した,負の活性化熱容量によって示された温度適応を示した.

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