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1,18-オクタデカンジオ酸-パクリタキセルとヒト血清アルブミンの抗腫瘍作用

Cassandra E Callmann1,2, Clare L M LeGuyader1, Spencer T Burton2

  • 1Department of Chemistry & Biochemistry , University of California San Diego , La Jolla , California 92093 , United States.

Journal of the American Chemical Society
|July 19, 2019
PubMed
まとめ

新しいパクリタキセル (PTX) プロドラッグであるODDA-PTXは,改善された薬物投与のためにヒト血清アルブミン (HSA) を利用する. このアルバミン結合戦略は,前臨床がんモデルにおける抗腫瘍効果と耐容性を高めます.

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