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Updated: Jan 21, 2026

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
10:58

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Published on: February 22, 2015

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グリオブラストーマの細胞状態,可塑性,遺伝学の統合モデル

Cyril Neftel1, Julie Laffy2, Mariella G Filbin3

  • 1Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Institute of Pathology, Faculty of Biology and Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, 1011, Switzerland.

Cell
|July 23, 2019
PubMed
まとめ

グリオブラストーマ細胞は4つの主要状態で存在し 遺伝学と腫瘍の微小環境の影響を受けます この研究は,膠芽細胞の細胞多様性と可塑性の統一モデルを提供します.

キーワード:
CDK4 についてEGFRNF1 についてPDGFRA についてIDHワイルドタイプグリオブラストーマの幹細胞グリオブラストーマのサブタイプ系統追跡単細胞RNAシーケンシング

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