関連する実験動画

Updated: Jan 20, 2026

Ubiquitin Chain Analysis by Parallel Reaction Monitoring
08:33

Ubiquitin Chain Analysis by Parallel Reaction Monitoring

Published on: June 17, 2020

4.0K

Ub-clipping を使用したユビキチンチェーンアーキテクチャの洞察

Kirby N Swatek1,2, Joanne L Usher1, Anja F Kueck1

  • 1Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.

Nature
|August 16, 2019
PubMed
まとめ

複雑なポリウビキチン鎖の構造を明らかにした. この技術は 枝分かれしたユビキチン鎖と共存する改変を定量化し,ユビキチンコードの理解を進める.

さらに関連する動画

Measuring Enzymatic Activity of Neurodevelopmental Disorder-Associated Deubiquitylating Enzymes via an In Vitro Ubiquitin Chain Cleavage Assay07:05

Measuring Enzymatic Activity of Neurodevelopmental Disorder-Associated Deubiquitylating Enzymes via an In Vitro Ubiquitin Chain Cleavage Assay

Published on: September 27, 2024

948
In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones11:36

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones

Published on: July 25, 2019

11.4K

関連する概念動画

Electron Transport Chains01:28

Electron Transport Chains

The final stage of cellular respiration is oxidative phosphorylation that consists of two steps: the electron transport chain and chemiosmosis. The electron transport chain is a set of proteins found in the inner mitochondrial membrane in eukaryotic cells. Its primary function is to establish a proton gradient that can be used during chemiosmosis to produce ATP and generate electron carriers, such as NAD+ and FAD, that are used in glycolysis and the citric acid cycle.
The ETC is comprised of...
111.7K
Polymer Classification: Architecture01:14

Polymer Classification: Architecture

Polymers are classified as linear or branched on the basis of their chain architecture. The polymer chains in linear polymers have a long chain-like structure with minimal to no branching at all. Even if a polymer features large substituent groups on the monomer, which appear as branches to the skeleton, it is not considered a branched polymer. A branched polymer contains secondary polymer chains that arise from the main polymer chain. The branching occurs when the polymer growth shifts from...
3.7K
Radical Chain-Growth Polymerization: Chain Branching01:17

Radical Chain-Growth Polymerization: Chain Branching

The skeletal structure of polymers synthesized via radical polymerization is always branched. For example, the polymerization of ethylene by radical polymerization results in a low-density grade of polyethylene with a heavily branched skeletal structure. Here, the radical site abstracts hydrogen from the growing chain, and the radical site shifts from the end (a primary carbon center) to anywhere within the growing chain (a secondary carbon center). Consequently, the part of the chain from the...
2.4K
The Chain Rule01:30

The Chain Rule

A system of interconnected gears provides a concrete physical interpretation of the Chain Rule in calculus. Consider three gears arranged in sequence, where the rotational speeds of the first, second, and third gears are represented by the variables x, z, and y, respectively. The first gear drives the second, and the second drives the third, so the motion of each gear depends on the one preceding it. This structure naturally leads to a two-stage variable relationship that can be analyzed using...
35
The Chain Rule: Problem Solving01:23

The Chain Rule: Problem Solving

The thermal expansion of a metal rod shows the application of the Chain Rule when one physical quantity depends on another that varies with time. As the rod is heated, its length changes according to linear thermal expansion, while the temperature of the system varies quadratically with time.For linear thermal expansion, the length L of the rod depends on temperature T such that the rate of change of length with respect to temperature is constant:where L0 = 2 m is the initial length of...
35
The Electron Transport Chain01:30

The Electron Transport Chain

The electron transport chain or oxidative phosphorylation is an exothermic process in which free energy released during electron transfer reactions is coupled to ATP synthesis. This process is a significant source of energy in aerobic cells, and therefore inhibitors of the electron transport chain can be detrimental to the cell's metabolic processes.
Inhibitors of the electron transport chain
Rotenone, a widely used pesticide, prevents electron transfer from Fe-S cluster to ubiquinone or Q...
19.7K