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Updated: Jun 14, 2026

Steady-state, Pre-steady-state, and Single-turnover Kinetic Measurement for DNA Glycosylase Activity
14:27

Steady-state, Pre-steady-state, and Single-turnover Kinetic Measurement for DNA Glycosylase Activity

Published on: August 19, 2013

Uracil DNA Glycosylaseにおけるグラウンドステート不安定化:基質における"タウトメリック・ストレイン"を忘れてはならない

Ranjita Das1, Erik A Vázquez-Montelongo2, G Andrés Cisneros2

  • 1Department of Chemistry , University of Houston , Houston , Texas 77204 , United States.

Journal of the American Chemical Society
|August 23, 2019
PubMed
まとめ

Uracil DNA glycosylase (UDG) は,珍しいタウトマーを模倣して uracil を不安定化し,その脱出グループ能力を高めます. この酵素誘発の分極化は DNA修復メカニズムを容易にする.

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