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Updated: Jan 20, 2026

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation
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細胞死経路における動物および植物TIRドメインによるNAD+分裂活動

Shane Horsefield1, Hayden Burdett1, Xiaoxiao Zhang2,3

  • 1School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.

Science (New York, N.Y.)
|August 24, 2019
PubMed
まとめ

ステリルアルファおよびTIRモチーフ含有1 (SARM1) および植物免疫受容体は,細胞死信号にToll/インタールイキン-1受容体 (TIR) ドメインを使用する. これらのTIRドメインはニコチナミドアデニン・ディヌクレオチド (NAD+) を分裂させ,動物と植物の保存メカニズムである.

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