関連する実験動画

Updated: Jan 20, 2026

Evaluating Leaf Responses to Microbial Secondary Metabolites Using A High-Throughput Format
05:51

Evaluating Leaf Responses to Microbial Secondary Metabolites Using A High-Throughput Format

Published on: December 5, 2025

418

微生物の代謝物は,粘膜と関連した不変のT細胞の胸膜の発達を制御する

François Legoux1, Déborah Bellet2, Celine Daviaud3,4

  • 1INSERM U932, PSL University, Institut Curie, Paris 75005, France. olivier.lantz@curie.fr francois.legoux@curie.fr.

Science (New York, N.Y.)
|August 31, 2019
PubMed
まとめ

コメンサル細菌の代謝産物,特に5- ((2- オックスプロピリデナミノ) - 6 - d- リビティラミノウラシル (5- OP- RU) は,粘膜関連不変性T細胞 (MAIT) の発育に不可欠である. これは腸内微生物群と 免疫細胞の成熟との 新しい関連を強調しています

さらに関連する動画

Intracranial Injection of Gut-Derived Microbial Metabolites in a Mouse Model01:55

Intracranial Injection of Gut-Derived Microbial Metabolites in a Mouse Model

Published on: August 7, 2025

379
A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants10:44

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants

Published on: August 9, 2019

7.6K

関連する概念動画

Evaluating Leaf Responses to Microbial Secondary Metabolites Using A High-Throughput Format05:51

Evaluating Leaf Responses to Microbial Secondary Metabolites Using A High-Throughput Format

This protocol describes a high-throughput approach for evaluating plant ion leakage, peroxidase activity, and callose production in the same sample.
418
Intracranial Injection of Gut-Derived Microbial Metabolites in a Mouse Model01:55

Intracranial Injection of Gut-Derived Microbial Metabolites in a Mouse Model

Source: Liou, C. et al. Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice. J. Vis. Exp. (2022).This video demonstrates the intracranial injection of short-chain fatty acids (SCFAs) in a freely moving mouse to study their effects on brain-mediated behavior. An injector cannula is inserted into a guide cannula implanted in the mouse brain. After recovery, the mouse acclimates in a novel cage. SCFAs are then administered, and locomotor behavior is...
379
A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants10:44

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants

This article describes a novel method to generate tumor antigen-specific induced pluripotent stem cell-derived thymic emigrants (iTE) by a three-dimensional (3D) thymic culture system. iTE are a homogenous subset of T cells closely related to naïve T cells with the capacity for proliferation, memory formation, and tumor...
7.6K
Using the Open-Source MALDI TOF-MS IDBac Pipeline for Analysis of Microbial Protein and Specialized Metabolite Data09:29

Using the Open-Source MALDI TOF-MS IDBac Pipeline for Analysis of Microbial Protein and Specialized Metabolite Data

IDBac is an open-source mass spectrometry-based bioinformatics pipeline that integrates data from both intact protein and specialized metabolite spectra, collected on cell material scraped from bacterial colonies. The pipeline allows researchers to rapidly organize hundreds to thousands of bacterial colonies into putative taxonomic groups, and further differentiate them based on specialized metabolite...
20.3K
Three-Dimensional Thymic Culture System to Generate iPSC-Derived Thymic Emigrants05:06

Three-Dimensional Thymic Culture System to Generate iPSC-Derived Thymic Emigrants

This video demonstrates a protocol for generating functional antigen-specific T cells from iPSC-derived immature T cells using a three-dimensional thymic culture system. Co-culturing the iPSC-derived immature T cells with endogenous lymphocyte-depleted mice fetal thymic lobes resulted in successful maturation of the T cells to form CD8αβ+ MHC class I+ iPSC-derived thymic emigrants...
576
Isolation, Identification, and Purification of Murine Thymic Epithelial Cells07:20

Isolation, Identification, and Purification of Murine Thymic Epithelial Cells

Here we describe an efficient method for isolation, identification, and purification of mouse thymic epithelial cells (TECs). The protocol can be utilized for studies of thymus function for normal T cell development, thymus dysfunction, and T cell...
33.3K