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Updated: Jan 20, 2026

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration
08:17

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration

Published on: February 27, 2018

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遺伝的統合失調症モデルにおけるネットワークと認知機能障害の長期的救済

Arghya Mukherjee1, Fernando Carvalho1, Stephan Eliez2

  • 1Friedrich Miescher Institute, 4058 Basel, Switzerland.

Cell
|September 3, 2019
PubMed
まとめ

マウスモデルでの統合失調症の治療は,青春期の後半に腹部海馬と中部前頭皮質のパルバルブミン (PV) ニューロンをターゲットにすることで,認知およびネットワークの欠陥を予防することができ,早期の治療介入が示唆されます.

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Author Spotlight: Improving Anesthesia Protocols for Enhanced Mouse Acupuncture Research03:26

Author Spotlight: Improving Anesthesia Protocols for Enhanced Mouse Acupuncture Research

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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia05:51

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

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A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration08:17

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This protocol describes a mouse model of orthopedic surgery that has been used to study mechanisms of postoperative neuroinflammation and behavioral changes, and when combined with parabiosis, to study tissue regeneration during...
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Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

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Acupuncture Treatment in a Mouse Model of Chronic Hypoxia-Induced Cognitive Dysfunction03:26

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Here, we describe a protocol for implementing mild anesthesia and acupuncture treatment on a chronic hypoxia mouse model and conducting behavioral tests to assess the cognitive alterations post-treatment.
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Molecular genetic strategy for finding de novo mutations causing common disorders such as autism and schizophrenia.
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Automated, Long-term Behavioral Assay for Cognitive Functions in Multiple Genetic Models of Alzheimer's Disease, Using IntelliCage06:46

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Fully automated system for measuring physiologically meaningful properties of the mechanisms mediating spatial localization, temporal localization, duration, rate and probability estimation, risk assessment, impulsivity, and the accuracy and precision of memory, in order to assess the effects of genetic and pharmacological manipulations on foundational mechanisms of cognition in...
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