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Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis
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Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis

Published on: January 7, 2017

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ATP-Aptamerのレドックス交換可能な結合特性

Yonatan Biniuri1, Guo-Feng Luo1, Michael Fadeev1

  • 1Institute of Chemistry, The Minerva Center for Biohybrid Complex Systems , The Hebrew University of Jerusalem , Jerusalem 91904 , Israel.

Journal of the American Chemical Society
|September 4, 2019
PubMed
まとめ

研究者は新しい酸化還元制御可能なアプタマースイッチを開発した. このメチレンブルー改変型アプタマーシステムは,ATPへの可逆的な"ON"/"OFF"結合を可能にし,分子相互作用を正確に制御します.

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