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Updated: Jan 20, 2026

Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency
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Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency

Published on: June 16, 2011

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インフルエンザAウイルスのRNAポリメラーゼの構造は,ウイルスゲノム複製の洞察を提供します

Haitian Fan1, Alexander P Walker1, Loïc Carrique2

  • 1Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.

Nature
|September 6, 2019
PubMed
まとめ

研究者はヒトと鳥のインフルエンザAポリメラーゼ (FluPolA) の構造を決定し,ウイルスのRNA複製に不可欠な二重体を形成する方法を明らかにした. この二分化を標的としたナノボディはウイルスの複製を阻害し,新しい抗ウイルス薬の標的を示唆した.

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