関連する実験動画

Updated: Jan 20, 2026

CRISPR-Mediated Reorganization of Chromatin Loop Structure
09:20

CRISPR-Mediated Reorganization of Chromatin Loop Structure

Published on: September 14, 2018

13.1K

ChAHP コンプレックスは,マウスのSINE 拡張から発生したCTCF サイトでのクロマチンのループに対抗します

Lucas J T Kaaij1, Fabio Mohn1, Robin H van der Weide2

  • 1Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.

Cell
|September 7, 2019
PubMed
まとめ

ChAHP複合体はCTCFと結合部位で競合し,クロマチンの組織に影響を与えます. この複合体は,転置可能な要素から新しいCTCFサイトを管理することによって,保存された空間クロマチン構造を維持するのに役立ちます.

キーワード:
3Dクロマチン構造ADNP についてCHD4 についてCTCF についてChAHP についてヘルスモートル・ヴァン・ダー・アア症候群Hi-C についてSINE B2 移行可能な要素クロマチンループ結束性

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