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Updated: Jan 19, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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二重C ((sp3) -H活性化により有効な (-) エピコシンGと (-) ロストラチンAの効率的かつ異なる全合成

Pierre Thesmar1, Olivier Baudoin1

  • 1Department of Chemistry , University of Basel , St. Johanns-Ring 19 , CH-4056 Basel , Switzerland.

Journal of the American Chemical Society
|September 27, 2019
PubMed
まとめ

研究者は, (-) - エピコシンGと (-) - ロストラチンAを含む複雑なディチオジケトピペラジンのためのスケーラブルな合成を開発した. この突破は 生物学的活性のある天然製品への 重要なアクセスを提供し 更に研究を進めています

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