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Updated: Jan 19, 2026

Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library
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Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library

Published on: January 14, 2020

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hCRBPIIドメイン交換ダイマーを新しいクラスのタンパク質スイッチに設計

Alireza Ghanbarpour1, Cody Pinger1, Rahele Esmatpour Salmani1

  • 1Department of Chemistry , Michigan State University , East Lansing , Michigan 48824 , United States.

Journal of the American Chemical Society
|September 27, 2019
PubMed
まとめ

研究者はドメイン交換ダイマーを使って 新種のタンパク質構成スイッチを設計した. このタンパク質の設計は,機能的なタンパク質のスイッチを作成するための新しいテンプレートを提供し,堅固なアロステリック反応を示しています.

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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions06:50

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

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Protein Complexes with Interchangeable Parts

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